Increases of IgA milk concentrations correlate with IgA2 increment

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Human milk IgA concentrations during the first year of lactation.

AIMS To measure the concentrations of total IgA in the milk secreted by both breasts, throughout the first year of lactation, in a cohort of Gambian mothers of infants at high risk of infection. SUBJECTS AND METHODS Sixty five women and their infants were studied monthly from the 4th to 52nd postpartum week. Samples of milk were obtained from each breast by manual expression immediately befor...

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To investigate the influence of breast feeding on mucosal immunity the concentrations and daily outputs of IgA and lactoferrin in urine were measured in 10 breast fed and 12 infants fed on formula milk at 6 and 12 weeks of age. The concentrations and outputs of secretory IgA in urine were significantly higher in the breast fed group by a factor of three. The secretion of IgA in urine by the bre...

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Increases in nitric oxide concentrations correlate strongly with body fat in obese humans.

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Supplemental β-carotene increases IgA-secreting cells in mammary gland and IgA transfer from milk to neonatal mice.

Mortality of neonates continues to be a major problem in humans and animals. IgA provides protection against microbial antigens at mucosal surfaces. Although β-carotene supplementation has been expected to enhance retinoic acid-mediated immune response in neonates, the exact mechanism by which β-carotene enhances IgA production is still unclear. We investigated the effect of supplemental β-caro...

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ژورنال

عنوان ژورنال: Journal of Clinical Laboratory Analysis

سال: 2001

ISSN: 0887-8013

DOI: 10.1002/jcla.1